Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. A Nature Research Journal. The actin and microtubule cytoskeletons play important roles in Golgi structure and function, but how they are connected remain poorly known.

We provide evidence that the fission events occur at a limited number of hotspots sites. The microtubule MT and actin cytoskeletons play important roles in Golgi structure and function. It is now well established that intact MT network and the minus-end MT dynein motor are required for maintaining the Golgi structure. MT depolymerization causes Golgi ribbon fragmentation and Golgi membranes redistribution near endoplasmic reticulum ER exit sites.

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